Clinical Trials
Lady Prelox® improves sexual function in post-menopausal women
A Bottari, G Belcaro, A Ledda, M R Cesarone, G Vinciguerra, A Di Renzo, S Stuard, M Dugall, L Pellegrini, S Errichi, G Gizzi, E Ippolito, A Ricci, M Cacchio, I Ruffini, F Fano, M Hosoi
The aim of this pilot, single-blinded study was to evaluate the efficacy of a proprietary, dietary supplement Lady Prelox® for supporting and improving sexual function in generally healthy, post-menopausal women. The Lady Prelox® and placebo control groups were comparable at inclusion with regard to the total Female Sexual Function Index (FSFI) score, as well as for the six individual FSFI domains, with 40 women (50.1 ± 3.1 years) and 43 women (51.2 ± 2.3 years), respectively.
Prevention of vaginal dryness in perimenopausal women. Supplementation with Lady Prelox®
Maria R Cesarone, Gianni Belcaro, Claudia Scipione, Valeria Scipione, Mark Dugall, Shu Hu, Roberto Cotellese, Beatrice Feragalli , Andrea Ledda
The aim of this pilot registry study was to use a standardized supplement (Lady Prelox®, Horphag Research) - including Pycnogenol®, l-arginine, L-citrulline and rose hip extract - to improve signs and symptoms associated with vaginal dryness in pre and post-menopausal healthy women. A group of women used only a standard management (SM) and a second group added Lady Prelox®. Four groups of women were included in the study. 34 pre-menopausal and 38 post-menopausal women took Lady Prelox®, four tablets daily for 8 weeks and 33 pre-menopausal women and 35 post-menopausal women served as controls.
Lady Prelox® improves sexual function in generally healthy women of reproductive age
A Bottari, G Belcaro, A Ledda, R Luzzi, M R Cesarone, M Dugall
This supplement study evaluates the Female Sexual Function Index (FSFI) of 100 healthy women (37 to 45 years) with moderate sexual dysfunction who underwent a management program of lifestyle, diet, exercise, and stress control. In association with the management program a group of these women also used the supplement Lady Prelox® in tablets (20 mg Pycnogenol® pine bark extract, 200 mg L-arginine, 200 mg L-citrulline and 50 mg Rosvita® rose hip extract) for eight weeks.
The Female Sexual Function Index (FSFI)-A Systematic Review of Measurement Properties
Koen I Neijenhuijs, Nienke Hooghiemstra, Karen Holtmaat, Neil K Aaronson, Mogens Groenvold, Bernhard Holzner, Caroline B Terwee, Pim Cuijpers, Irma M Verdonck-de Leeuw
A systematic search was performed of Embase, Medline, and Web of Science for studies that investigated measurement properties of the FSFI-19 or FSFI-6 up to April 2018. Data were extracted and analyzed according to COnsensus-based Standards for the selection of health Measurement INstruments (COSMIN) guidelines. Evidence was categorized into sufficient, insufficient, inconsistent, or indeterminate, and quality of evidence as very high, high, moderate, or low.